Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Higher Mental Functions of the Brain: Language01:10

Higher Mental Functions of the Brain: Language

1.8K
Language is a system of communication that allows the expression of thoughts, ideas, and feelings. The brain processes language in both hemispheres.
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...
1.8K
Association Areas of the Cortex01:21

Association Areas of the Cortex

6.8K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.8K
Visual Agnosia01:12

Visual Agnosia

442
Visual agnosia is a condition characterized by the inability to recognize visually presented objects despite having normal vision. For instance, a person with visual agnosia can describe the shape and color of an object but cannot identify or name it. This impairment does not affect their visual field, acuity, color vision, brightness discrimination, language, or memory. An example of this condition in a social setting is someone at a dinner party asking for "that silver thing with a round...
442
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

5.1K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
5.1K
Language and Cognition01:27

Language and Cognition

504
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
504
Amnesia01:13

Amnesia

219
Amnesia is a condition marked by long-term memory loss, which impairs the ability to recall past events or create new memories.
The severity and duration of memory loss vary depending on the type and underlying cause. Amnesia is classified into two main types: retrograde and anterograde.
Retrograde amnesia is marked by the loss of memories formed before the onset of the condition. Patients may recall distant past events but often forget those occurring shortly before the incident.
Anterograde...
219

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Object and action naming in adults and aged people with Down syndrome.

Dementia & neuropsychologia·2025
Same author

Assessment of language abilities and functionality in adults and elders with Down syndrome.

Dementia & neuropsychologia·2025
Same author

An Overview of the Effects of Lithium on Alzheimer's Disease: A Historical Perspective.

Pharmaceuticals (Basel, Switzerland)·2025
Same author

Somatostatin interneurons and the pathogenesis of Alzheimer's disease.

Neural regeneration research·2025
Same author

Subcortical Aphasia: An Update.

Current neurology and neuroscience reports·2024
Same author

Electroconvulsive therapy for treating patients with agitation and related behavioral disorders due to dementia: a systematic review.

Dementia & neuropsychologia·2023
Same journal

The Noradrenergic Brain in Parkinson's Disease.

Current neurology and neuroscience reports·2026
Same journal

Mapping the Silent Onset of Parkinson's Disease: Monoamine Imaging in the Era of the Race for Preclinical Intervention.

Current neurology and neuroscience reports·2026
Same journal

Functional and Structural Brain Imaging Correlates of Treatment Response in Functional Movement Disorder.

Current neurology and neuroscience reports·2026
Same journal

Astrocytopathy in Wernicke Encephalopathy and Neuromyelitis Optica Spectrum Disorder. Pathogenic Differences With Occasional Clinical and Neuroimaging Overlap. A Review.

Current neurology and neuroscience reports·2026
Same journal

When is the Radiologically Isolated Syndrome already Multiple Sclerosis According to the 2024 McDonald Criteria?

Current neurology and neuroscience reports·2026
Same journal

Assessment and Management of Post-traumatic Headache.

Current neurology and neuroscience reports·2026
See all related articles

Related Experiment Video

Updated: Oct 12, 2025

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
10:15

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Published on: July 2, 2013

18.0K

Subcortical Aphasia.

Marcia Radanovic1, Victor N Almeida2

  • 1Laboratorio de Neurociencias (LIM-27), Faculdade de Medicina, Departamento e Instituto de Psiquiatria, Hospital das Clínicas HCFMUSP, Universidade de São Paulo, Rua Dr. Ovídio Pires de Campos, 785, SP, 05403-903, São Paulo, Brazil. marciaradanovic@gmail.com.

Current Neurology and Neuroscience Reports
|November 24, 2021
PubMed
Summary
This summary is machine-generated.

Subcortical structures like the basal ganglia and thalamus are crucial for language processing. Recent findings highlight their roles in specific language deficits and suggest advanced neuroimaging will further clarify these complex relationships in aphasiology.

Keywords:
AphasiaBasal gangliaLanguageSubcorticalThalamus

More Related Videos

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.9K
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.7K

Related Experiment Videos

Last Updated: Oct 12, 2025

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia
10:15

Utilizing Repetitive Transcranial Magnetic Stimulation to Improve Language Function in Stroke Patients with Chronic Non-fluent Aphasia

Published on: July 2, 2013

18.0K
Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping
13:12

Translational Brain Mapping at the University of Rochester Medical Center: Preserving the Mind Through Personalized Brain Mapping

Published on: August 12, 2019

45.9K
Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains
12:28

Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging Brains

Published on: June 3, 2020

17.7K

Area of Science:

  • Neuroscience
  • Linguistics
  • Neurology

Background:

  • Subcortical structures, including the basal ganglia and thalamus, have been historically implicated in language processing.
  • Theoretical frameworks for non-thalamic aphasia include the disconnection hypothesis, direct basal ganglia involvement, and cortical deafferentation.
  • Thalamic aphasia is often attributed to diaschisis, with specific thalamic nuclei linked to distinct language deficits.

Purpose of the Study:

  • To review theoretical frameworks of subcortical aphasias.
  • To discuss recent findings on the role of the basal ganglia and thalamus in language processing.
  • To explore the impact of deep brain stimulation, neurophysiology, and aphasiology on understanding these conditions.

Main Methods:

  • Review of existing literature on subcortical aphasias and theoretical frameworks.
  • Analysis of recent findings in neurophysiology and aphasiology.
  • Consideration of neuroimaging techniques, including tractography and connectivity studies.

Main Results:

  • Non-thalamic aphasias may result from cortical hypoperfusion.
  • Specific thalamic nuclei (pulvinar/LP, AV/VA) are associated with lexical-semantic and word selection deficits.
  • Characterizing subcortical aphasias remains challenging, but neuroimaging offers promising avenues for research.

Conclusions:

  • The basal ganglia and thalamus play significant, though complex, roles in language.
  • Advanced neuroimaging techniques are essential for further elucidating the neural basis of subcortical aphasias.
  • Continued research in aphasiology, neurophysiology, and deep brain stimulation will refine our understanding of subcortical language networks.