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Mood Reactive Disorders among COVID-19 Inpatients: Experience from a Monocentric Cohort

Vito Fiore1, Andrea De Vito1, Chiara Fanelli1

  • 1Infectious and Tropical Diseases Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, Sassari, Italy.

Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre
|November 24, 2021
PubMed

Insights

Depressive symptoms are common in coronavirus disease 2019 (COVID-19) inpatients, with over 40% experiencing them. While symptoms improved after discharge, early psychological evaluation is recommended for COVID-19 patients.

Area of Science:

  • Psychiatry
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) is a global health crisis.
  • Mental health impacts of COVID-19 require thorough investigation.
  • Depressive symptoms are a significant concern for hospitalized patients.

Purpose of the Study:

  • To assess the prevalence and severity of depressive symptoms in COVID-19 inpatients.
  • To evaluate changes in depressive symptoms after hospital discharge.
  • To identify factors associated with depressive symptom severity in COVID-19 patients.

Main Methods:

  • A cohort of 48 COVID-19 inpatients in Italy was studied.
  • The Beck Depression Inventory-II (BDI-II) was administered at admission (T0) and 1 week post-discharge (T1).
  • A BDI-II score of 20 or higher indicated clinically significant depressive symptoms.

Main Results:

  • 43.7% of patients reported clinically significant depressive symptoms at T0.
  • Moderate to severe depressive symptoms were observed in 33.4% of patients at T0.
  • A significant improvement in BDI-II scores was noted from T0 to T1 (p < 0.0001).
  • Kidney failure and roommate's death were associated with greater mood disorder severity.

Conclusions:

  • Depressive symptoms are prevalent in COVID-19 inpatients.
  • Hospitalized COVID-19 patients may be at increased risk for reactive mood disorders.
  • Early psychological support and interventions to improve sleep quality are beneficial for COVID-19 patients.
Abstract

Keywords:
Coronavirus disease 2019DepressionMental healthMood disordersSARS-CoV-2

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