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Melanoma metastasis to the bladder: A case report
Raj A Kumar1, Nikhil Batra2, Jon Frankel3
1Catherine & Joseph Aresty Department of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Urology Case Reports
|November 25, 2021
Summary
Malignant melanoma rarely presents as bladder metastasis clinically. Autopsy studies suggest higher rates, indicating many cases go undiagnosed, as seen in this case report.
Area of Science:
- Oncology
- Urology
- Pathology
Background:
- Malignant melanoma metastasis to the bladder is infrequently diagnosed in clinical practice, with limited reported cases.
- Autopsy findings suggest a higher prevalence of bladder metastasis in melanoma patients than clinically recognized.
Observation:
- A patient presented with severe anemia and gross hematuria, indicative of urinary tract pathology.
- Imaging (CT scan) identified a significant bladder mass (2.7 cm).
- Cystoscopy confirmed the presence of the bladder mass.
Findings:
- Transurethral resection of the bladder tumor was performed.
- Pathological examination confirmed the tumor to be metastatic malignant melanoma.
Implications:
- This case highlights the importance of considering metastatic melanoma in patients with unexplained hematuria and bladder masses.
- Increased clinical awareness and diagnostic vigilance may improve the detection rate of this rare presentation.
- Further research into the mechanisms and clinical significance of melanoma metastasis to the bladder is warranted.

