Related Experiment Video

Updated: Oct 12, 2025

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

1.8K

Left atrial strain: A novel "biomarker" for chronic kidney disease patients?

Ana Tanasa1,2, Laura Tapoi1,2, Carina Ureche1,2

  • 1Cardiovascular Diseases Institute "Prof. Dr. George I.M. Georgescu", Iasi, Romania.

Echocardiography (Mount Kisco, N.Y.)
|November 25, 2021
PubMed

Insights

Left atrial strain is a promising new marker for predicting cardiovascular events in chronic kidney disease patients. This measure can identify patients at high risk and those with reduced exercise capacity.

Area of Science:

  • Cardiology
  • Nephrology
  • Biomarkers

Background:

  • Cardiovascular disease (CVD) and chronic kidney disease (CKD) are closely linked, significantly increasing cardiovascular risk.
  • Current risk prediction algorithms often underestimate this risk in CKD patients.
  • There is a need for novel biomarkers to improve risk stratification in this population.

Purpose of the Study:

  • To review the existing evidence on the role of left atrial strain in patients with chronic kidney disease.
  • To assess its utility in diagnosing and predicting adverse cardiovascular outcomes.

Main Methods:

  • Review of current literature on left atrial strain in CKD.
  • Analysis of studies correlating left atrial strain with cardiovascular events and exercise capacity.

Main Results:

  • Left atrial size and function reflect left ventricular filling pressures.
  • Increased left atrial volume index and impaired left atrial strain are independent predictors of adverse cardiovascular events.
  • Left atrial strain impairment precedes changes in volume, predicting both diastolic and systolic dysfunction.
  • Left atrial strain can identify CKD patients with reduced exercise capacity.

Conclusions:

  • Left atrial strain is a valuable prognostic marker in CKD patients.
  • It offers potential clinical applications in risk stratification and rehabilitation programs for renal patients.

Keywords:
chronic kidney diseaseleft atrial strainleft atrial volume

More Related Videos

Assessment of Vascular Function in Patients With Chronic Kidney Disease08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

16.4K
A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion09:02

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion

Published on: February 2, 2021

4.6K

Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
147
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
82
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
146
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
392
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
106
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
43