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Updated: Oct 12, 2025

A Step Beyond BRET: Fluorescence by Unbound Excitation from Luminescence FUEL
Published on: May 23, 2014
Recent advances in dioxaborine-based fluorescent materials for bioimaging applications.
1Laboratoire de Bioimagerie et Pathologies, UMR 7021, CNRS/Université de Strasbourg, 74 route du Rhin, 67401 Illkirch-Graffenstaden, France. mayeul.collot@unistra.fr.
Dioxaborine-based fluorescent materials (DBFM) show great promise for bioimaging due to their unique photophysical properties. This review highlights recent DBFM advancements and applications in detecting biomolecules, ions, and environmental factors.
Area of Science:
- Materials Science
- Biotechnology
- Chemistry
Background:
- Fluorescent materials are crucial for bioimaging advancements.
- Dioxaborine-based fluorescent materials (DBFM) are gaining attention for their unique properties.
Purpose of the Study:
- To review recent advances in DBFM for bioimaging applications.
- To provide a comprehensive insight into the assets and limitations of DBFM.
Main Methods:
- Literature review of recent studies on DBFM.
- Analysis of DBFM applications in detecting various analytes and environments.
Main Results:
- DBFM exhibit excellent photophysical properties: high extinction coefficients, quantum yields, near-infrared emission, photostability, and two-photon absorption.
- DBFM have been developed into fluorescent probes for biomolecules (DNA, proteins), small molecules (cysteine, H2O2, oxygen), ions, and environmental parameters (polarity, viscosity).
- DBFM are also utilized in polymer and nanomaterial-based bioimaging.
Conclusions:
- DBFM offer significant advantages for diverse bioimaging applications.
- Further development is needed to overcome current limitations and fully exploit DBFM potential.
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