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Updated: Oct 12, 2025

Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses
Published on: March 29, 2017
The brain remembers where and how inflammation struck
1Circuits for Emotion Research Group, Max Planck Institute of Neurobiology, Martinsried, Germany; Department of Emotion Research, Max Planck Institute of Psychiatry, Munich, Germany.
Abstract:
Our immune system and brain interact on multiple scales, but how the brain represents and remembers immune challenges remains unclear. In this issue of Cell, Koren et al. (2021) reveal that the brain's insular cortex stores information about inflammation in the body. Strikingly, these immunological "memory engrams" can restore the initial disease state when reactivated.
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