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Double Delayed Enhancement: Concomitant Cardiac Amyloidosis and Acute Coronary Embolism

Talha Ahmed1,2, Nils P Johnson1,2, Anju Bhardwaj1,2

  • 1The University of Texas Health Science Center at Houston, Houston, Texas, US.

Methodist Debakey Cardiovascular Journal
|November 26, 2021
PubMed

Insights

Hereditary cardiac amyloidosis (CA) significantly raises the risk of blood clots in the heart. This case highlights a patient with CA experiencing chest pain due to a co-occurring acute coronary embolism.

Area of Science:

  • Cardiology
  • Genetics
  • Cardiovascular Medicine

Background:

  • Hereditary cardiac amyloidosis (CA) is an uncommon cause of nonischemic cardiomyopathy.
  • Patients with CA face an elevated risk of developing intracardiac thrombi.

Observation:

  • A patient presented with symptoms of chest pain and acute myocardial infarction.
  • Diagnostic workup revealed the patient had both CA and acute coronary embolism.

Findings:

  • The case demonstrates a rare presentation of acute myocardial infarction secondary to coronary embolism in a patient with undiagnosed hereditary cardiac amyloidosis.
  • This highlights the potential for thromboembolic events in the context of CA.

Implications:

  • Early recognition of CA is crucial for managing thromboembolic risk.
  • This case underscores the importance of considering uncommon etiologies for myocardial infarction, particularly in patients with underlying cardiomyopathies.
  • Further research into the mechanisms linking CA and embolic events may improve patient outcomes.

Keywords:
cardiac amyloidosiscardiac magnetic resonance imagingcoronary angiographycoronary embolismdelayed enhancement

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