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Adherence to the paediatric immunisation schedule in England
Jorgen Bauwens1,2, Simon de Lusignan3,4, Julian Sherlock3
1University of Basel, Switzerland.
Vaccine: X
|November 26, 2021
Summary
Timeliness of paediatric vaccinations is crucial for disease prevention. While many first doses are timely, subsequent doses often show delays or are given too soon, impacting protection.
Area of Science:
- Public Health
- Epidemiology
- Immunology
Background:
- Optimal protection against vaccine-preventable diseases requires adequate paediatric immunisation coverage and adherence to schedules.
- Timeliness of vaccinations is a critical component of adherence, influencing vaccine efficacy and population immunity.
Purpose of the Study:
- To assess the timeliness of routine paediatric vaccinations within the NHS schedule.
- To identify factors influencing adherence to paediatric immunisation schedules, including gender, region, and socioeconomic status.
Main Methods:
- Utilised immunisation data from the Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) for 2008-2018.
- Analysed vaccination types, doses, and dates for over 6 million vaccinations in 1 million children.
- Calculated adherence to schedule for each vaccine and dose, analysing differences by gender, NHS region, and Index of Multiple Deprivation (IMD) quintiles.
Main Results:
- 75% of first paediatric vaccine doses were administered within recommended timeframes (1-2 months).
- Approximately 50% of subsequent vaccine doses were administered timely, with significant proportions given too early or too late.
- Immunisation schedule adherence showed slight improvement with decreasing deprivation, and differences between genders and NHS regions were generally small.
Conclusions:
- Efforts are needed to improve the timeliness of paediatric vaccinations to ensure adequate protection against vaccine-preventable diseases.
- A combined measure of coverage and adherence is proposed to better reflect community protection against vaccine-preventable diseases.
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