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Updated: Oct 12, 2025

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COVID-19 Detection Using Deep Learning Algorithm on Chest X-ray Images.

Shamima Akter1, F M Javed Mehedi Shamrat2, Sovon Chakraborty3

  • 1Department of Bioinformatics and Computational Biology, George Mason University, Fairfax, VA 22030, USA.

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|November 27, 2021
PubMed
Summary
This summary is machine-generated.

This study introduces a modified MobileNetV2 deep learning model for accurate COVID-19 detection using chest X-rays. The proposed method achieved 98% accuracy, outperforming existing Convolutional Neural Network (CNN) models.

Keywords:
CNNCOVID-19Mobilenetv2chest X-ray imagemodified MobileNetV2performance evaluation

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Pulmonology

Background:

  • COVID-19, a severe respiratory illness, necessitates rapid and accurate diagnostic tools.
  • Chest X-ray imaging is crucial for diagnosing COVID-19 due to its primary impact on the lungs.
  • Automated screening methods can enhance early detection and minimize healthcare professional exposure.

Purpose of the Study:

  • To develop and evaluate an automatic deep learning classification method for COVID-19 detection from chest X-ray images.
  • To compare the performance of eleven existing Convolutional Neural Network (CNN) models for COVID-19 classification.
  • To propose a modified MobileNetV2 model for improved accuracy and efficiency in COVID-19 diagnosis.

Main Methods:

  • A dataset of 3616 COVID-19 and 10,192 healthy chest X-rays was augmented to 26,000 images each.
  • Data preprocessing involved histogram equalization, spectrum, grays, cyan, and NCLAHE normalization.
  • Eleven CNN models (VGG16, VGG19, MobileNetV2, InceptionV3, NFNet, ResNet50, ResNet101, DenseNet, EfficientNetB7, AlexNet, GoogLeNet) were initially employed, followed by modification of MobileNetV2.

Main Results:

  • The modified MobileNetV2 model achieved the highest accuracy of 98% in classifying COVID-19 from chest X-rays.
  • Pre-trained MobileNetV2, VGG19, and ResNet101 models showed accuracies of 97%, 95%, and 95%, respectively.
  • The proposed model demonstrated the shortest compilation time (2 h, 50 min, 21 s) and statistically significant performance.

Conclusions:

  • The proposed modified MobileNetV2 deep learning model offers a highly accurate and efficient method for COVID-19 detection using chest X-rays.
  • This automated approach surpasses existing methods in identifying infection symptoms from radiographic images.
  • The findings support the clinical utility of AI-driven tools for rapid COVID-19 screening.