Oxytocin Receptor Gene Polymorphism in Lactating Dogs
Asahi Ogi1,2, Valentina Naef2, Filippo Maria Santorelli2
1Department of Veterinary Sciences, University of Pisa, 56124 Pisa, Italy.
Animals : an Open Access Journal From MDPI
|November 27, 2021
Summary
Genetic variations in the oxytocin receptor (OXTR) gene influence maternal behavior in dogs. Labrador Retrievers with a specific OXTR gene variant showed higher oxytocin levels and maternal care, impacting puppy development.
Area of Science:
- Animal Behavior
- Genetics
- Neuroscience
Background:
- Genetic variations in the oxytocinergic system influence mammalian social behavior.
- Polymorphic variants of the oxytocin receptor (OXTR) gene are linked to behavioral variations in humans and dogs.
Purpose of the Study:
- To investigate the correlation between salivary oxytocin levels, maternal behavior, and a specific OXTR gene variant (rs8679684) in lactating Labrador Retriever dogs.
Main Methods:
- Salivary oxytocin levels were measured in 19 lactating Labrador Retrievers.
- Maternal behavior was assessed.
- Genotyping was performed for the OXTR gene variant rs8679684.
Main Results:
- Dogs carrying at least one copy of the minor A allele of rs8679684 exhibited higher salivary oxytocin levels.
- These dogs also displayed increased maternal care compared to homozygous T allele carriers.
- The OXTR gene variant is associated with variations in maternal care and oxytocin levels.
Conclusions:
- Findings suggest a link between OXTR gene variants and maternal behavior in dogs.
- This could inform strategies for selecting dams with optimal maternal care traits.
- Understanding these genetic influences is crucial for canine welfare and breeding programs.
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