Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What are Estimates?01:06

What are Estimates?

6.1K
It isn't easy to measure a parameter such as the mean height or the mean weight of a population. So, we draw samples from the population and calculate the mean height or mean weight of the individuals in the sample. This sample data acts as a representative measure of the population parameter. These sample statistics are known as estimates. 
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
6.1K
Types of Errors: Detection and Minimization01:12

Types of Errors: Detection and Minimization

4.8K
Error is the deviation of the obtained result from the true, expected value or the estimated central value. Errors are expressed in absolute or relative terms.
Absolute error in a measurement is the numerical difference from the true or central value. Relative error is the ratio between absolute error and the true or central value, expressed as a percentage.
Errors can be classified by source, magnitude, and sign. There are three types of errors: systematic, random, and gross.
Systematic or...
4.8K
Systematic Error: Methodological and Sampling Errors01:15

Systematic Error: Methodological and Sampling Errors

4.3K
In the case of systematic errors, the sources can be identified, and the errors can be subsequently minimized by addressing these sources. According to the source, systematic errors can be divided into sampling, instrumental, methodological, and personal errors.
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
4.3K
Random Error01:04

Random Error

3.5K
Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
3.5K
Distributions to Estimate Population Parameter01:26

Distributions to Estimate Population Parameter

4.4K
The accurate values of population parameters such as population proportion, population mean, and population standard deviation (or variance) are usually unknown. These are fixed values that can only be estimated from the data collected from the samples. The estimates of each of these parameters are sample proportion, the sample mean, and sample standard deviation (or variance). To obtain the values of these sample statistics, data are required that have particular distribution and central...
4.4K
Prediction Intervals01:03

Prediction Intervals

2.4K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Linking Nanoscale Film Properties to Electrochemical Response in Cytochrome P450 Membrane Enzyme Films.

ACS measurement science au·2026
Same author

Eliciting Unreported Subgroup-Specific Survival from Aggregate Randomized Controlled Trial Data.

Medical decision making : an international journal of the Society for Medical Decision Making·2025
Same author

ACR Appropriateness Criteria® Staging and Follow-Up of Primary Liver Cancer.

Journal of the American College of Radiology : JACR·2025
Same author

Double vein embolization before major hepatectomy: A single-center experience.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2025
Same author

Nivolumab plus Ipilimumab in Microsatellite-Instability-High Metastatic Colorectal Cancer.

The New England journal of medicine·2024
Same author

Accelerating Progress Towards the 2030 Neglected Tropical Diseases Targets: How Can Quantitative Modeling Support Programmatic Decisions?

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2024

Related Experiment Video

Updated: Oct 12, 2025

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
09:23

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans

Published on: August 16, 2017

8.3K

Information-Corrected Estimation: A Generalization Error Reducing Parameter Estimation Method.

Matthew Dixon1, Tyler Ward2

  • 1Department of Applied Mathematics, Illinois Institute of Technology, Chicago, IL 60616, USA.

Entropy (Basel, Switzerland)
|November 27, 2021
PubMed
Summary
This summary is machine-generated.

We introduce Information-Corrected Estimation (ICE), a new method to reduce generalization error in supervised machine learning. ICE improves model performance by directly maximizing a corrected likelihood function, outperforming existing methods.

Keywords:
entropygeneralization errorinformation criteriaoverfitting

More Related Videos

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K
Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

7.1K

Related Experiment Videos

Last Updated: Oct 12, 2025

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
09:23

Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans

Published on: August 16, 2017

8.3K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.7K
Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity
07:28

Psychophysically-anchored, Robust Thresholding in Studying Pain-related Lateralization of Oscillatory Prestimulus Activity

Published on: January 21, 2017

7.1K

Area of Science:

  • Machine Learning
  • Statistical Learning Theory

Background:

  • Supervised machine learning models are often universal approximators where parameter values are less important than out-of-sample performance.
  • Traditional model estimation focuses on parameter bias/variance, which may not correlate with predictive accuracy.
  • Ridge regression (L2 regularization) is common but requires hyperparameter tuning and can be sensitive to parameterization.

Purpose of the Study:

  • To introduce a novel objective function, Information-Corrected Estimation (ICE), designed to minimize KL divergence-based generalization error in supervised learning.
  • To provide a theoretically sound method for improving model generalization across a broad range of models.
  • To experimentally validate ICE's effectiveness against established methods like Maximum Likelihood Estimation and L2 regularization.

Main Methods:

  • Developed Information-Corrected Estimation (ICE) by defining a corrected likelihood function.
  • Theoretically analyzed ICE for its effectiveness under mild regularity conditions.
  • Experimentally compared ICE against Maximum Likelihood Estimation and L2 regularization on finite datasets.

Main Results:

  • ICE is theoretically proven to be effective for a wide class of models.
  • Experimental results demonstrate significant reductions in generalization error using ICE compared to Maximum Likelihood Estimation.
  • ICE also showed superior performance over L2 regularization in reducing generalization error.

Conclusions:

  • Information-Corrected Estimation (ICE) offers a theoretically grounded and experimentally validated approach to enhance supervised learning model generalization.
  • ICE provides a direct method to minimize KL divergence, leading to improved out-of-sample predictive performance.
  • The proposed method represents a significant advancement over traditional Maximum Likelihood Estimation and L2 regularization techniques.