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Updated: Oct 12, 2025

Quantification of the Potential Impact of Glyphosate-Based Products on Microbiomes
Published on: January 10, 2022
Glyphosate Use, Toxicity and Occurrence in Food
Diogo Soares1, Liliana Silva1, Sofia Duarte1,2
1LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Polo III, Azinhaga de Stª Comba, 3000-548 Coimbra, Portugal.
Glyphosate, the world's most used herbicide, is under scrutiny for potential human health risks due to its widespread agricultural application and presence in food. Scientific consensus on its safety remains divided, prompting public health concerns.
Area of Science:
- Agricultural Science
- Toxicology
- Food Safety
Background:
- Glyphosate is the most widely used herbicide globally, with increasing consumption over recent decades.
- Its persistence in soil and potential presence in food have raised public health concerns.
- A lack of scientific consensus exists regarding glyphosate's safety and health implications.
Purpose of the Study:
- To review the current literature on glyphosate usage patterns.
- To examine the toxicological profile of glyphosate.
- To investigate the occurrence of glyphosate in various food samples.
Main Methods:
- Systematic literature review of glyphosate use, toxicity studies, and food residue analysis.
- Analysis of reported glyphosate levels in diverse food matrices.
- Evaluation of regulatory limits and detected concentrations.
Main Results:
- Glyphosate use has significantly increased worldwide.
- Evidence suggests glyphosate can occur in food samples, sometimes exceeding legal limits.
- Toxicological data presents a controversial picture of its health effects.
Conclusions:
- The widespread use and detection of glyphosate in food, occasionally at violative levels, warrant attention.
- Suspected toxic effects necessitate further investigation and public health awareness.
- Ongoing debate highlights the need for continued research into glyphosate's long-term impacts.
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