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Intraoperative Guidance Using Hyperspectral Imaging: A Review for Surgeons
Manuel Barberio1,2, Sara Benedicenti2, Margherita Pizzicannella2
1Institute for Research against Digestive Cancer (IRCAD), 67091 Strasbourg, France.
Diagnostics (Basel, Switzerland)
|November 27, 2021
Summary
Hyperspectral imaging (HSI) offers contactless biochemical analysis for distinguishing tissue types and identifying pathologies. This overview aims to introduce HSI to surgeons for improved intraoperative guidance and clinical practice.
Area of Science:
- Medical Imaging
- Biochemical Analysis
- Optical Imaging
Background:
- Hyperspectral imaging (HSI) is an advanced optical technique combining digital photography and spectroscopy.
- It enables non-destructive, contactless biochemical analysis of living tissues.
- HSI provides molecular-level insights into tissue composition, differentiating healthy from pathological states.
Purpose of the Study:
- To provide clinical surgeons with an overview of hyperspectral imaging (HSI).
- To highlight HSI's capabilities, limitations, and future potential for intraoperative guidance.
- To increase awareness of HSI within the surgical community.
Main Methods:
- Review of hyperspectral imaging principles and applications in medicine.
- Analysis of HSI's use as an intraoperative guidance tool across surgical disciplines.
- Discussion of current challenges and future research directions for HSI in surgery.
Main Results:
- HSI allows for objective, contrast-free discrimination between tissue types and health/pathology states.
- Recent advancements have enabled HSI's application in the operating room as a guidance tool.
- Despite its potential, HSI is not yet widely adopted in routine surgical practice.
Conclusions:
- Hyperspectral imaging holds significant promise for enhancing intraoperative guidance.
- Further education and integration are needed to overcome barriers to routine clinical adoption.
- HSI has the potential to revolutionize surgical decision-making and patient outcomes.

