Adipose-Derived Stem Cell: "Treat or Trick".

Area of Science:

• Regenerative Medicine
• Stem Cell Biology
• Tissue Engineering

Background:

• Stem cells offer significant therapeutic benefits for various diseases.
• Adipose-derived stem cells (ADSCs) are mesenchymal stem cells easily harvested in large volumes.
• ADSCs possess differentiation potential and secrete bioactive factors crucial for tissue repair.

Purpose of the Study:

• To review the current research on adipose-derived stem cells (ADSCs) for disease treatment.
• To evaluate the potential benefits and risks associated with ADSC therapy.
• To highlight the dual "trick or treat" effect of ADSCs in medical applications.

Main Methods:

• Literature review of preclinical and clinical studies on ADSCs.
• Analysis of ADSC properties, including differentiation capacity and secretome.
• Evaluation of reported outcomes and safety profiles in ADSC-treated conditions.

Main Results:

• ADSCs exhibit multipotency and secrete growth factors, cytokines, and hormones.
• These factors contribute to metabolic regulation, energy balance, and homeostasis.
• Evidence suggests ADSCs play a role in tissue repair and regeneration.

Conclusions:

• Adipose-derived stem cells (ADSCs) hold potential for regenerative therapies.
• Further research is essential to clarify the efficacy and safety of ADSCs.
• Understanding the "trick or treat" nature of ADSCs is critical for clinical translation.