Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

470
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
470
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

645
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
645

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychiatric boarding: what is it, how do we recognise it, and what are the implications?

Irish journal of psychological medicine·2024
Same author

Effects of Cannabinoid Exposure during Neurodevelopment on Future Effects of Drugs of Abuse: A Preclinical Perspective.

International journal of molecular sciences·2021
Same author

Efficacy of Phytocannabinoids in Epilepsy Treatment: Novel Approaches and Recent Advances.

International journal of environmental research and public health·2021
Same author

A Critical Review of the Role of the Cannabinoid Compounds Δ<sup>9</sup>-Tetrahydrocannabinol (Δ<sup>9</sup>-THC) and Cannabidiol (CBD) and their Combination in Multiple Sclerosis Treatment.

Molecules (Basel, Switzerland)·2020

Related Experiment Video

Updated: Oct 12, 2025

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

828

Cannabidiol Does Not Cause Significant Changes to Working Memory Performance in the N-Back Task.

Éamon Jones1, Styliani Vlachou1

  • 1Neuropsychopharmacology Division, Behavioural Neuroscience Laboratory, School of Psychology, Faculty of Science and Health, Dublin City University, Glasnevin, Dublin 9, D09 Y074 Dublin, Ireland.

Pharmaceuticals (Basel, Switzerland)
|November 27, 2021
PubMed
Summary

Cannabidiol (CBD) use does not significantly impact working memory (WM) functioning. This study found no statistically significant differences in cognitive performance on the N-back task between CBD users and non-users.

Keywords:
N-back taskcannabidiolcannabinoidcognitionworking memory

More Related Videos

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

4.9K
Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
13:34

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

8.5K

Related Experiment Videos

Last Updated: Oct 12, 2025

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

828
Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

4.9K
Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
13:34

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Published on: June 4, 2020

8.5K

Area of Science:

  • Neuroscience
  • Pharmacology

Background:

  • Cannabis has historical uses, with over 100 identified cannabinoids.
  • Cannabidiol (CBD) is recognized for anti-inflammatory and anxiolytic properties.
  • Limited research exists on CBD's specific effects on cognitive functions like working memory.

Purpose of the Study:

  • To investigate the impact of CBD on working memory (WM) performance.
  • To determine if CBD use causes statistically significant differences in WM functioning.
  • To expand the existing literature on cannabinoid effects on cognition.

Main Methods:

  • 54 participants (26 CBD users, 28 non-users) completed an online survey and N-back task.
  • The N-back task assessed working memory by measuring accuracy and response time.
  • Multivariate analysis of covariance controlled for duration and reason for CBD use.

Main Results:

  • No statistically significant differences in response time or accuracy were found between CBD users and non-users.
  • Results support the hypothesis that CBD does not alter working memory functioning.
  • Cognitive performance on the N-back task remained unaffected by CBD use in this cohort.

Conclusions:

  • Current findings suggest CBD does not significantly affect working memory.
  • Further research is needed to explore long-term CBD effects on cognitive functions.
  • This study contributes to understanding CBD's role in cognitive performance.