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Updated: Oct 12, 2025

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

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A Study on Synthesis and Upscaling of 2'-O-AECM-5-methyl Pyrimidine Phosphoramidites for Oligonucleotide Synthesis

Kristina Karalė1,2, Martin Bollmark2, Rouven Stulz1,3

  • 1Department of Biosciences and Nutrition, Karolinska Institutet, Neo, 141 57 Huddinge, Sweden.

Molecules (Basel, Switzerland)
|November 27, 2021
PubMed

Keywords:
2′-O-(N-(aminoethyl)carbamoyl)methyl modification5-methylcytidine5-methyluridinealkylationmonoacetylationoligonucleotidesphase transfer catalysis (PTC)

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