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Assessment of the Substance Antioxidative Profile by Hyaluronan, Cu(II) and Ascorbate
Katarína Valachová1, Ladislav Šoltés1
1Centre of Experimental Medicine, Institute of Experimental Pharmacology and Toxicology, Slovak Academy of Sciences, Dúbravská Cesta 9, SK-84104 Bratislava, Slovakia.
Abstract:
In the minireview presented here, the authors discuss the evaluation of inhibitory effect of substances in the phases of initiation and propagation of high-molar-mass hyaluronan oxidative degradation. The experimental approach should be considered as original since on using a simple experimental assay it is possible to prove both the so-called "preventive" and "chain-breaking" antioxidant activity of investigated water-soluble endo- or exogenous substances.
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