Factors Affecting Post-Stroke Depression in Acute Ischemic Stroke Patients after 3 Months

Area of Science:

• Neurology
• Psychiatry
• Public Health

Background:

• Post-stroke depression (PSD) affects one-third of stroke survivors, increasing mortality and recurrence risks.
• Limited research exists on PSD prognostic and relieving factors, particularly environmental influences.
• Understanding these factors is crucial for improving patient recovery and quality of life.

Purpose of the Study:

• To identify risk factors for developing PSD three months post-stroke.
• To determine factors associated with the improvement of early PSD within three months.
• To inform strategies for managing and recovering from PSD.

Main Methods:

• Retrospective study of 227 acute ischemic stroke patients.
• Assessed depressive status using Hamilton Depression Rating Scale (HDRS) at admission and three months.
• Analyzed clinical and laboratory data, including National Institute of Health Stroke Scale (NIHSS) scores.

Main Results:

• Admission HDRS score and hospitalization period were significant risk factors for PSD.
• NIHSS score at discharge and admission HDRS score predicted depression improvement.
• Higher admission HDRS scores and longer hospital stays increased PSD risk.

Conclusions:

• Hospitalization period, an environmental factor, is important in managing PSD.
• Factors related to depression improvement can guide PSD recovery strategies.
• Early identification of risk factors and predictors of improvement is key for PSD management.