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A Review on Biphasic Calcium Phosphate Materials Derived from Fish Discards
Liviu Duta1, Gabriela Dorcioman1, Valentina Grumezescu1
1Lasers Department, National Institute for Lasers, Plasma and Radiation Physics, 077125 Magurele, Romania.
Nanomaterials (Basel, Switzerland)
|November 27, 2021
Summary
Fish waste can be transformed into valuable biphasic calcium phosphate (BCP) materials for biomedical applications. This review explores processing effects on BCP properties for bone tissue engineering and other uses.
Area of Science:
- Materials Science
- Biomaterials Engineering
- Biotechnology
Background:
- Growing demand for bone grafts and scaffolds in orthopedics due to increased life expectancy and bone injuries.
- Calcium phosphate (CaP) bioceramics, particularly biphasic calcium phosphates (BCP) composed of hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP), are favored for their biocompatibility and osteoconductivity.
- Limited research on sustainable and cost-effective sources for BCP production.
Purpose of the Study:
- To review the production of biphasic calcium phosphate (BCP) materials from fish waste (discards).
- To discuss the potential of these sustainable BCPs for biomedical and other applications.
- To analyze the impact of processing conditions on the properties of fish-derived BCPs.
Main Methods:
- Compilation and analysis of existing literature on BCP production from fish waste.
- Discussion of the transformation of fish discards (heads, bones, skins, viscera) into BCP materials.
- Evaluation of morphological, compositional, structural, mechanical, and biological properties.
Main Results:
- Fish waste is a viable, cost-effective, and sustainable source for producing BCP materials.
- Processing conditions significantly influence the properties of the resulting BCPs.
- Fish-derived BCPs show promise for applications in bone tissue engineering, orthopedics, and dentistry.
Conclusions:
- Utilizing fish discards for BCP production offers significant economic and environmental benefits.
- Tailoring processing conditions allows for the optimization of fish-derived BCP properties for specific applications.
- This approach presents an innovative solution for healthcare improvement using alternative biomaterials.
