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Updated: Oct 11, 2025

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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
18.4K
Nutrition and melanoma prevention.
Madeline E DeWane1, Neda Shahriari2, Jane M Grant-Kels3
1University of Connecticut School of Medicine, Farmington, Connecticut, USA.
Clinics in Dermatology
|November 27, 2021
Summary
Dietary factors may influence melanoma risk, with some compounds showing promise in lab studies and population data. However, more human trials are needed to confirm these nutritional links to skin cancer prevention.
Area of Science:
- Nutritional Science
- Dermatology
- Oncology
Background:
- Growing interest in diet's role in melanoma risk.
- Numerous dietary compounds investigated for potential effects.
Purpose of the Study:
- To review selected dietary factors and nutritional elements impacting melanoma risk.
- To synthesize current evidence on diet and skin cancer.
Main Methods:
- Literature review of various dietary compounds.
- Analysis of in vitro and epidemiological study findings.
Main Results:
- Some dietary compounds show promising in vitro evidence.
- Epidemiological studies suggest associations between certain nutrients and reduced melanoma risk.
Conclusions:
- Evidence for dietary components in melanoma risk reduction is largely based on preliminary data.
- Randomized controlled trials in humans are lacking and needed for definitive conclusions.
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