Evaluation of Pulmonary Structure and Function in Patients with Cystic Fibrosis from Electrical Impedance Tomography...

Electrical impedance tomography (EIT) is a medical imaging technique in which low frequency, low amplitude electromagnetic fields applied through electrodes on the skin are used to compute the conductivity and/or permittivity inside the body and form functional images from the reconstructed values. This work describes methods of computing EIT-derived surrogate measures of pulmonary function and identifying regions of air trapping and consolidation from functional EIT images. These methods were developed for pediatric patients with cystic fibrosis, for whom a real-time non-ionizing imaging modality can be of great benefit for monitoring disease progression or a pulmonary exacerbation.