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Updated: Oct 11, 2025

Breath Collection from Children for Disease Biomarker Discovery
Published on: February 14, 2019
Effects of inhalation aromatherapy as a complementary therapy in pediatric patients in the clinical practice: A
Francisca A Sánchez1, Javiera R Rosales1, Pablo R Godoy1
1School of Nursing, Faculty of Medicine, Universidad Austral de Chile, Valdivia, Chile.
Insights
Inhalational aromatherapy showed no significant effects on pain, nausea, vomiting, or behavior in hospitalized children. More high-quality research is needed to confirm its effectiveness in pediatric care.
Area of Science:
- Pediatric Nursing
- Complementary and Alternative Medicine
- Evidence-Based Practice
Background:
- Inhalation aromatherapy is a complementary therapy used in various clinical settings.
- Limited evidence exists regarding its effectiveness in pediatric care.
Purpose of the Study:
- To evaluate the efficacy of inhalational aromatherapy for hospitalized pediatric patients.
Main Methods:
- A systematic review of randomized controlled trials and quasi-experimental studies was conducted.
- Searches were performed across multiple databases (Medline, Web of Science, Scopus, etc.).
- Risk of bias was assessed using standardized scales (Down and Black 2020, RoB 2020 CLARITY, ROBINS-I 2020).
Main Results:
- Nine studies met inclusion criteria; most were randomized controlled trials.
- No significant effects of inhalation aromatherapy were found for pain, nausea, vomiting, or behavioral/emotional variables.
- Pain was the most frequently measured outcome in the included studies.
Conclusions:
- Current evidence on the effectiveness of inhalation aromatherapy in pediatric care is inconclusive.
- Further high-quality studies with robust methodology, blinding, and adequate sample sizes are necessary.
- More research is required to establish the role of aromatherapy in pediatric settings.
Background:
Inhalation aromatherapy is a complementary therapy in different clinical settings, but there is little evidence about its effectiveness in childcare.
Objective:
To assess the effectiveness of inhalational aromatherapy in the care of hospitalized pediatric patients.
Methods:
Systematic review of clinical trials and quasi-experimental studies, based on PRISMA recommendations, searching Medline, Web of Science, Scopus, SciELO, LILACS, CINAHL, Science Direct, EBSCO, and updated databases. The Down and Black 2020, RoB 2020 CLARITY, and ROBINS-I 2020 scales were used through the Distiller SR software to verify the studies' internal validity and risk of bias.
Results:
From 446 articles identified, 9 fulfilled the inclusion criteria. Seven were randomized controlled trials (RCTs), one pilot RCT, and one non-randomized quasi-experimental trial. Different outcomes were analyzed, with pain being the most frequently measured variable. None of the 6 studies that evaluated pain showed significant effects with inhalation aromatherapy. Additionally, non-significant effects were found regarding nausea, vomiting, and behavioral/emotional variables.
Conclusions:
The findings are still inconclusive, and more evidence is required from future studies with high methodological quality, blinding, and adequate sample sizes.
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