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Related Experiment Video

Updated: Oct 11, 2025

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Applying implementation science to improve care for familial hypercholesterolemia.

Laney K Jones1, Ross C Brownson2,3, Marc S Williams1

  • 1Genomic Medicine Institute, Geisinger, Danville, PA, USA.

Current Opinion in Endocrinology, Diabetes, and Obesity
|November 28, 2021
PubMed
Summary

Improving familial hypercholesteremia (FH) care requires effective implementation strategies. This review maps current FH care improvements to the Expert Recommendations for Implementing Change (ERIC) framework, identifying gaps for future development.

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Area of Science:

  • Implementation Science
  • Cardiovascular Medicine
  • Public Health

Background:

  • Familial hypercholesteremia (FH) management necessitates translating evidence-based guidelines into clinical practice.
  • Effective implementation strategies are crucial for improving FH care delivery.

Purpose of the Study:

  • To review and map existing implementation strategies for improving familial hypercholesteremia (FH) care.
  • To identify gaps in current implementation approaches using the Expert Recommendations for Implementing Change (ERIC) compilation.

Main Methods:

  • A literature search identified 153 articles on improving FH care between November 2018 and July 2021.
  • 37 relevant articles were mapped to strategies within the Expert Recommendations for Implementing Change (ERIC) compilation.
  • Analysis focused on the utilization of implementation science theories and the addressing of health disparities.

Main Results:

  • Key implementation strategies identified include assessing readiness, monitoring quality, forming clinical teams, facilitating data relay, and involving patients.
  • Only 8 of the 37 studies utilized an implementation science theory, model, or framework.
  • Few studies explicitly addressed health disparities or equity in FH care.

Conclusions:

  • Mapping FH care strategies to the ERIC compilation provides a structured overview of current implementation efforts.
  • Significant opportunities exist for developing new implementation strategies to address unaddressed aspects of FH care, including equity.