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Diffused coronary involvement in Takayasu arteritis with concomitant malignancy

Inbar Nardi-Agmon1,2, Ashraf Hamdan3,4, Alon Eisen3,4

  • 1Cardiology Division, Rabin Medical Center - Beilinson Hospital, 39 Zabotinski st., 4941492, Petach Tikva, Israel. inbaragmon@gmail.com.

Clinical Rheumatology
|November 28, 2021
PubMed

Insights

This case study highlights a young patient with Takayasu arteritis and extensive coronary disease, who also had Hodgkin

Area of Science:

  • Cardiology
  • Rheumatology
  • Oncology

Background:

  • Large vessel vasculitis (LVV) involves inflammation of major arteries, including coronary arteries.
  • Coronary artery disease in systemic vasculitis leads to significant morbidity and mortality.

Observation:

  • A young patient presented with extensive coronary disease, diagnosed as Takayasu arteritis.
  • Concurrently, the patient was diagnosed with Hodgkin's lymphoma.

Findings:

  • Literature review identified ten prior cases of malignancies associated with Takayasu arteritis.
  • This case underscores the complexity of managing concurrent hematological malignancy with Takayasu arteritis and extensive coronary arteritis.

Implications:

  • Effective management requires a multidisciplinary team approach.
  • Optimizing clinical outcomes for both conditions is crucial.
  • Further research into the link between vasculitis and malignancy may be warranted.

Keywords:
Coronary artery diseaseMalignancy and large vessel vasculitisTakayasu arteritis

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