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CLE peptides: critical regulators for stem cell maintenance in plants
Xiu-Fen Song1,2, Xiu-Li Hou3, Chun-Ming Liu4,5,6
1Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Planta
|November 29, 2021
Summary
Plant CLE peptides are crucial for maintaining stem cell populations in various plant tissues. These signaling molecules regulate cell fate and development, with conserved roles across species, though their complex interactions present research challenges.
Area of Science:
- Plant Biology
- Developmental Biology
- Molecular Signaling
Background:
- Plant CLE (CLAVATA3/Embryo Surrounding Region) peptides act as critical signaling molecules.
- They regulate stem cell homeostasis, cell fate determination, and physiological responses in plants.
- These peptides are involved in maintaining meristems (shoot and root) and vascular bundles.
Purpose of the Study:
- To summarize the known functions of plant CLE peptides in stem cell regulation.
- To highlight the roles of specific CLE peptides in different plant tissues.
- To discuss the evolutionary conservation and research challenges associated with CLE peptides.
Main Methods:
- Literature review and synthesis of existing research on plant CLE peptides.
- Analysis of conserved CLE peptide orthologs across different plant species.
- Examination of functional studies on specific CLE peptides in model plants like Arabidopsis.
Main Results:
- CLE peptides regulate stem cell number and differentiation in shoot apical meristems (SAM) and root apical meristems (RAM).
- Specific CLE peptides like TDIF promote vascular bundle development, while others like CLE25 and CLE45 influence phloem differentiation.
- CLV3 orthologs are conserved in diverse plant species, indicating a fundamental role in stem cell maintenance.
Conclusions:
- Plant CLE peptides are essential, complex, and conserved regulators of stem cell maintenance.
- Understanding CLE peptide signaling is vital for plant development and physiology.
- Further research is needed to overcome challenges in studying CLE peptide function due to genetic redundancy and rapid evolution.
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