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Updated: Oct 11, 2025

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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Occipital bending in migraine with visual aura
Esra Özkan1, Yasemin Gürsoy-Özdemir1,2
1Koç University Research Center for Translational Medicine, Koç University Hospital, Istanbul, Turkey.
Headache
|November 29, 2021
Summary
Occipital bending (OB) is more common in migraine with visual aura patients. This brain asymmetry may play a role in the pathophysiology of visual aura in migraine.
Area of Science:
- Neuroscience
- Radiology
- Neurology
Background:
- Occipital bending (OB) is a unique brain asymmetry where one occipital pole crosses the midline.
- OB has been linked to psychiatric conditions, suggesting it's more than an anatomical variation.
- Brain structural differences exist between migraine with aura and without aura, but OB's role is unexplored.
Purpose of the Study:
- To investigate the frequency of occipital bending (OB) in patients experiencing migraine with visual aura.
- To compare OB prevalence between migraine with aura and migraine without aura patient groups.
Main Methods:
- Retrospective cohort study analyzing data from 2016-2021.
- Included 84 migraine patients with and without visual aura who underwent cranial MRI.
- Data sourced from Koç University Hospital's outpatient headache clinic database.
Main Results:
- The overall prevalence of OB in migraine patients was 33.3%.
- OB was significantly more frequent in patients with migraine with visual aura (57.1%) compared to those without aura (25.4%).
- The odds ratio for OB in migraine with visual aura was 3.9 (p=0.015).
Conclusions:
- Occipital bending (OB) occurs twice as frequently in patients with migraine with visual aura.
- The increased prevalence suggests potential pathophysiological implications of OB in migraine with visual aura.
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