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Distance Wagner tree refinement as a heuristic approach to character-based initial tree construction.

Ward C Wheeler¹

¹Division of Invertebrate Zoology, American Museum of Natural History, 200 Central Park West, New York, NY, 10024, USA.

Cladistics : the International Journal of the Willi Hennig Society

|November 29, 2021

Summary

The distance Wagner procedure offers a fast method for constructing phylogenetic trees. This enhanced method allows for tree refinement, improving initial tree generation for further analysis.

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A Practical Guide to Phylogenetics for Nonexperts

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Published on: February 5, 2014

Area of Science:

Phylogenetics
Computational Biology
Evolutionary Biology

Background:

The distance Wagner procedure is a rapid method for phylogenetic tree construction.
Original formulations lacked refinement capabilities using common search operations like SPR and TBR.

Purpose of the Study:

To extend the distance Wagner method to incorporate refinement of initial trees.
To evaluate the performance of the extended distance Wagner as a heuristic search procedure.

Main Methods:

Extension of the distance Wagner method to allow refinement of trees generated by the four-point condition.
Evaluation using unaligned sequences and combined source datasets within a parsimony framework.

Main Results:

The extended distance Wagner procedure successfully generates refined initial trees.
Both original and refined distance Wagner methods are rapid and effective heuristic tools.

Conclusions:

The extended distance Wagner procedure is a valuable heuristic for generating initial phylogenetic trees.
This method facilitates subsequent character-based analyses, enhancing phylogenetic inference.