Related Experiment Video
Updated: Oct 11, 2025

Production and Characterization of Human Macrophages from Pluripotent Stem Cells
Published on: April 16, 2020
[Induction and differentiation of induced pluripotent stem cells into macrophages: a review]
Xinchun Yang1, Xiaolong Wu1, Jinlian Hua1
1Shaanxi Stem Cell Engineering and Technology Research Center, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, Shaanxi, China.
Induced pluripotent stem cells (iPSCs) are a type of cells similar to embryonic stem cells but produced by reprogramed somatic cells. Through in vitro differentiation of iPSCs, we can interrogate the evolution history as well as the various characteristics of macrophages. iPSCs derived macrophages are not only a good model for drug screening, but also an important approach for immunotherapy. This review summarizes the advances, challenges, and future directions in the field of iPSCs-derived macrophages.
Induced pluripotent stem cells (iPSCs) are a type of cells similar to embryonic stem cells but produced by reprogramed somatic cells. Through in vitro differentiation of iPSCs, we can interrogate the evolution history as well as the various characteristics of macrophages. iPSCs derived macrophages are not only a good model for drug screening, but also an important approach for immunotherapy. This review summarizes the advances, challenges, and future directions in the field of iPSCs-derived macrophages.
More Related Videos
11:19Human Microglia-like Cells: Differentiation from Induced Pluripotent Stem Cells and In Vitro Live-cell Phagocytosis Assay using Human Synaptosomes
Published on: August 18, 2022
10:52Differentiation and Characterization of Osteoclasts from Human Induced Pluripotent Stem Cells
Published on: March 22, 2024