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Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Related Experiment Video

Updated: Oct 11, 2025

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

United airway disease.

Angela Klain¹, Cristiana Indolfi², Giulio Dinardo³

¹Department of Woman, Child and of General and Specialized Surgery, University of Campania 'Luigi Vanvitelli', Naples, Italy. klainangela95@gmail.com.

Acta Bio-Medica : Atenei Parmensis

|November 29, 2021

Summary

The nose and lungs function as a unit, meaning allergic rhinitis and asthma treatments can improve both conditions. This review explores airway interactions and their therapeutic implications.

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Area of Science:

Immunology
Respiratory Medicine
Otolaryngology

Background:

The nose and lungs are anatomically and functionally linked.
Allergic rhinitis and asthma frequently co-occur, supporting the 'one airway, one disease' concept.
Shared pathophysiological and immunological mechanisms underlie upper and lower airway diseases.

Purpose of the Study:

To review the scientific evidence on upper and lower airway interactions.
To analyze the therapeutic and preventive implications of new findings.
To highlight the 'one airway, one disease' principle in clinical practice.

Main Methods:

Literature review of recent scientific evidence.
Critical analysis of existing research.
Synthesis of findings related to airway interactions.

Main Results:

Evidence supports a strong connection between upper and lower airways.
Treating one condition positively impacts the other.
New insights offer potential for integrated treatment strategies.

Conclusions:

The 'one airway, one disease' model is clinically relevant.
Future therapies should consider the integrated nature of airway diseases.
Prevention strategies may benefit from a unified approach.