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Quantifying Remission Probability in Type 2 Diabetes Mellitus.

Sanjay Kalra¹, Ganapathi Bantwal², Nitin Kapoor^3,4

¹Department of Endocrinology, Bharti Hospital, Karnal 132001, India.

Clinics and Practice

|November 29, 2021

Summary

Type 2 diabetes mellitus (T2DM) remission is achievable through lifestyle changes, surgery, and medication. Achieving normal diabetic parameters is a viable therapeutic goal, but long-term efficacy requires further study.

Keywords:

T2DM remission bariatric surgery lifestyle interventions reversal type 2 diabetes mellitus

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Area of Science:

Endocrinology
Metabolic Disorders
Public Health

Background:

Type 2 diabetes mellitus (T2DM) is a chronic, progressive condition linked to severe health issues and mortality.
The concept of T2DM remission, normalizing diabetic indicators, is gaining recognition in global health guidelines.

Purpose of the Study:

To review current strategies for achieving T2DM remission.
To evaluate T2DM remission as a therapeutic goal and potential alternative to costly treatments.

Main Methods:

Narrative review of existing literature.
Discussion of various intervention strategies including lifestyle modifications, physical activity, bariatric surgery, medical nutrition therapy, and non-insulin glucose-lowering medications.

Main Results:

Multiple validated models exist for quantifying T2DM remission.
Favorable clinical evidence supports T2DM remission as a therapeutic objective.
Various interventions show promise for achieving remission.

Conclusions:

T2DM remission is a recognized and achievable therapeutic goal.
Implementation in routine practice needs validation through long-term studies on intervention efficacy.