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Updated: Oct 11, 2025

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Cryoablation in Locoregional Management of Complex Unresectable Chest Neoplasms
Roberto Iezzi1,2, Andrea Contegiacomo1, Alessandro Posa1
1Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Istituto di Radiologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, L.go A Gemelli 8, 00168 Rome, Italy.
Rationale And Objectives:
The aim of our retrospective study was to assess the safety and feasibility of cryoablation in high-risk patients with complex chest neoplastic lesions.
Materials And Methods:
Twenty patients with complex chest malignancies, both primary and secondary, located in the mediastinum, lung, and chest wall, underwent percutaneous CT-guided cryoablation treatments. Procedural success as well as complications were evaluated.
Results:
A total of 24 neoplastic lesions were treated (mean diameter: 27 mm; range: 7-54 mm). Technical success was obtained in all patients, without major complications or intraprocedural death. A pneumothorax not requiring a drainage tube placement was registered in 50% of patients, while 3/24 patients had a grade 3 pneumothorax requiring a chest tube placement.
Conclusion:
Percutaneous CT-guided cryoablation seems a safe and feasible treatment for complex thoracic lesions.

