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Updated: Oct 11, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
A Novel Breast Cancer Diagnosis Scheme With Intelligent Feature and Parameter Selections
S Punitha1, Thompson Stephan2, Amir H Gandomi3
1Department of Computer Science Engineering, Karunya Insitute of Technology and Sciences, Tamilnadu, India.
This study introduces two novel hybrid Artificial Bee Colony (ABC) algorithms, HABC and Hybrid ABC, for improved automated breast cancer diagnosis. Hybrid ABC-RP achieved 99.54% accuracy, enhancing early detection and patient survival rates.
Area of Science:
- Computational intelligence
- Biomedical engineering
- Machine learning for healthcare
Background:
- Breast cancer diagnosis relies on early detection for improved patient survival rates.
- Manual diagnosis methods are prone to human error, inaccuracies, and time constraints.
- Artificial Neural Networks (ANNs) offer powerful automated diagnosis capabilities.
Purpose of the Study:
- To propose two novel hybrid Artificial Bee Colony (ABC) optimization algorithms, HABC and Hybrid ABC.
- To enhance the exploration and exploitation capabilities of standard ABC algorithms.
- To improve automated breast cancer diagnosis through optimized ANN models.
Main Methods:
- Hybridizing ABC with Artificial Immune System (HABC) and Bacterial Foraging Optimization (Hybrid ABC).
- Applying HABC and Hybrid ABC for concurrent feature selection and ANN parameter optimization.
- Utilizing back-propagation algorithms (Resilient Back-propagation, Levenberg-Marquardt, Gradient Descent) for ANN tuning.
Main Results:
- HABC-RP achieved 99.14% accuracy; Hybrid ABC-RP reached 99.54% accuracy.
- Hybrid ABC-RP demonstrated high sensitivity (99.08%), specificity (99.81%), and precision (99.38%).
- The proposed methods resulted in high accuracy with low complexity ANN structures.
Conclusions:
- The Hybrid ABC-RP algorithm offers superior performance in breast cancer diagnosis with high accuracy and low complexity.
- Concurrent feature selection and ANN parameter tuning are crucial for accurate breast cancer diagnosis.
- The developed hybrid algorithms outperform existing breast cancer diagnosis systems and show future potential for tumor segmentation and classifier tuning.
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