Comparative clinicopathological and bacteriological studies in schistosomiasis mansoni

Area of Science:

• Gastroenterology
• Infectious Diseases
• Pathology

Background:

• Colonic schistosomiasis (mansoniisis) is a significant parasitic infection.
• Understanding its clinicopathological manifestations across different stages is crucial for effective management.

Purpose of the Study:

• To investigate the clinicopathological, endoscopic, radiological, and bacteriological patterns of colonic schistosomiasis in Egyptian males.
• To determine the pattern of colonic and urinary enterobacteria and serum antisalmonella agglutinins in various stages of the disease.

Main Methods:

• Study included 50 male Egyptian inpatients with active colonic schistosomiasis.
• Patients were categorized into three groups (A, B, C) based on hepatosplenomegaly stage.
• Evaluations included clinicopathological, endoscopic, radiological, and bacteriological assessments.

Main Results:

• Clinical presentations varied, including dysentery, rectal bleeding, and anaemia.
• Oesophageal varices (19.8%) and colonic polyps (25% in group A) were observed.
• Bilharzia ova counts were highest in group A, with significant granulation tissue and mucosal hypertrophy in groups A and B.

Conclusions:

• Clinicopathological, endoscopic, and bacteriological findings correlate with the stage of hepatosplenomegaly in colonic schistosomiasis.
• Hematoxylin and eosin staining is effective for diagnosis, with no evidence of fungal or fibrinoid deposits.