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Published on: June 11, 2019
Magnetic Resonance Imaging for Cerebral Micro-embolizations During Minimally Invasive Mitral Valve Surgery
Cristina Barbero1, Mauro Rinaldi2, Giovanni Marchetto2
1Department of Cardiovascular and Thoracic Surgery, Città della Salute e della Scienza, University of Turin, Turin, Italy. cristina.barbero@unito.it.
Abstract:
The role of aortic clamping techniques on the occurrence of neurological complications after right mini-thoracotomy mitral valve surgery is still debated. Brain injuries can occur also as silent cerebral micro-embolizations (SCM), which have been linked to significant deficits in physical and cognitive functions. Aims of this study are to evaluate the overall rate of SCM and to compare endoaortic clamp (EAC) with trans-thoracic clamp (TTC). Patients enrolled underwent a pre-operative, a post-operative, and a follow-up MRI. Forty-three patients were enrolled; EAC was adopted in 21 patients, TTC in 22 patients. Post-operative SCM were reported in 12 cases (27.9%). No differences between the 2 groups were highlighted (23.8% SCM in the EAC group versus 31.8% in the TTC). MRI analysis showed post-operative SCM in nearly 30% of selected patients after right mini-thoracotomy mitral valve surgery. Subgroup analysis on different types of aortic clamping showed comparable results. CLINICAL RELEVANCE: The rate of SCM reported in the present study on patients undergoing minimally invasive MVS and RAP is consistent with data in the literature on patients undergoing cardiac surgery through median sternotomy and antegrade arterial perfusion. Moreover, no differences were reported between EAC and TTC: both the aortic clamping techniques are safe, and the choice of the surgical setting to adopt can be really done according to the patient's characteristics.
Insights
Silent cerebral micro-embolizations (SCM) after minimally invasive mitral valve surgery occur in about 30% of patients. Both endoaortic clamp and trans-thoracic clamp techniques showed comparable safety and SCM rates.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Medical Imaging
Background:
- Neurological complications, including silent cerebral micro-embolizations (SCM), are a concern after mitral valve surgery.
- The impact of different aortic clamping techniques on SCM in minimally invasive procedures remains unclear.
Purpose of the Study:
- To determine the overall incidence of SCM following right mini-thoracotomy mitral valve surgery.
- To compare the rates of SCM between endoaortic clamp (EAC) and trans-thoracic clamp (TTC) techniques.
Main Methods:
- Prospective study involving 43 patients undergoing minimally invasive mitral valve surgery.
- Pre-operative, post-operative, and follow-up MRI scans were used to detect SCM.
- Patients were divided into two groups: EAC (n=21) and TTC (n=22).
Main Results:
- Post-operative SCM were identified in 12 patients (27.9% overall incidence).
- No significant difference in SCM rates was observed between the EAC group (23.8%) and the TTC group (31.8%).
- MRI analysis confirmed SCM in approximately 30% of patients, with comparable results between clamping methods.
Conclusions:
- Minimally invasive mitral valve surgery is associated with a notable rate of SCM, consistent with findings in traditional sternotomy approaches.
- Both EAC and TTC are safe aortic clamping techniques for this procedure, with no difference in SCM occurrence.
- Surgical approach selection should be individualized based on patient characteristics rather than clamping technique preference.
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