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Cryptic Presentation of Disseminated Cryptococcosis.
Vijairam Selvaraj1, Kwame Dapaah-Afriyie1, Himmat Grewal2
1Division of Hospital Medicine, The Miriam Hospital; Warren Alpert Medical School of Brown University, Providence, RI.
Rhode Island Medical Journal (2013)
|November 30, 2021
Summary
Cryptococcosis is a serious fungal infection affecting immunocompromised individuals. This case highlights disseminated cryptococcosis presenting as a flank mass in a young woman.
Area of Science:
- Mycology
- Infectious Diseases
- Immunology
Background:
- Cryptococcosis is a significant global invasive fungal infection.
- It predominantly affects individuals with compromised immune systems, including those with HIV/AIDS, diabetes, and transplant recipients.
- Clinical presentation varies based on the primary organ affected, with potential for multi-organ involvement.
Purpose of the Study:
- To report a rare presentation of disseminated cryptococcosis.
- To emphasize the importance of considering fungal infections in immunosuppressed patients with unusual masses.
- To describe a case of cryptococcosis presenting as an enlarging flank mass.
Main Methods:
- Case report of a young female patient.
- Clinical presentation and diagnostic workup.
- Imaging and histopathological analysis for confirmation.
Main Results:
- The patient presented with an enlarging flank mass.
- Disseminated cryptococcosis was diagnosed.
- The infection occurred in the context of underlying immunosuppression.
Conclusions:
- Disseminated cryptococcosis can manifest with atypical presentations, such as flank masses.
- Immunosuppression is a critical risk factor for invasive fungal infections like cryptococcosis.
- Prompt diagnosis and management are crucial for patients with cryptococcosis, regardless of presentation.
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