[Vitamin D deficiency in elderly with arterial hypertension and left ventricular diastolic dysfunction.]

The aim of the study was to evaluate the relationship between serum vitamin D deficiency and the risk of diastolic dysfunction in elderly patients with arterial hypertension. The study included 162 elderly patients (mean age 65,4±5,2 years) with arterial hypertension. The first group consisted of 67 patients with hypertension without vitamin D deficiency, the second-95 patients with hypertension with deficiency. It was revealed that the patients with vitamin D deficiency in the blood serum were significantly older (Δ7,3%, p<0,05), had a higher body mass index (Δ9,6%, p<0,05), a shorter distance in the 6-minute walk test (Δ10,4%, p<0,05), and more often (72,6%) had left ventricular diastolic dysfunction (LV DD). Patients with hypertension with LV DD in the presence of vitamin D deficiency in serum had a worse metabolic profile - they had higher values of total cholesterol (Δ15,7%, p<0,05), triglycerides (Δ15,2%, p<0,05), the НOMA-IR index (Δ12%, p<0,05) and lower HDL values (Δ11,9%, p<0,05). In patients with hypertension with LV DD in the presence of vitamin D deficiency, the quality of life is lower than in patients with adequate levels of it. Conclusions. Elderly patients with hypertension had a slight difference in the incidence of LV DD between the study groups with different vitamin D status. However, elderly patients with hypertension with serum vitamin D deficiency had more pronounced disorders of LV diastolic dysfunction, lipid and carbohydrate metabolism. The quality of life according to the SF-36 questionnaire in elderly patients with hypertension with vitamin D deficiency in the blood serum was significantly lower than in the group with adequate vitamin D content.