Related Experiment Video
Updated: Aug 18, 2026

06:19
Isolation of Circulating Tumor Cells in an Orthotopic Mouse Model of Colorectal Cancer
Published on: July 18, 2017
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Using Circulating Tumor DNA for Colon Cancer Adjuvant Therapy: To Be or Not to Be?
Van K Morris1, Thomas J George2,3
1Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. vkmorris@mdanderson.org.
Abstract:
Detection of circulating tumor DNA (ctDNA) postoperatively is prognostic for recurrence for patients with stage III colon cancer. Those with sustained undetectable ctDNA will likely be cured. Eradication of minimal residual disease (per ctDNA clearance) with chemotherapy did not occur in most ctDNA-positive patients and led to eventual disease relapse.See related article by Henriksen et al., p. 507.

