Related Experiment Video
Updated: Oct 11, 2025

An In vitro System to Gauge the Thrombolytic Efficacy of Histotripsy and a Lytic Drug
Published on: June 4, 2021
EFFECTIVENESS OF DEEP VENOUS THROMBOSIS PREVENTION IN TOTAL HIP ARTHROPLASTY
Victor Martins Manfredi1, Matheus Bittencourt Machado1, Nícolas Giorgini Barbato1
1Ifor Hospital, Institute of Fractures, Orthopedics and Rehabilitation, São Bernardo do Campo, SP, Brazil.
Insights
This study demonstrates the high efficacy of a Deep Venous Thrombosis (DVT) prophylaxis protocol in total hip arthroplasty (THA) patients, with only a 1.09% complication rate. The protocol is essential for preventing DVT after THA.
Area of Science:
- Orthopedic Surgery
- Vascular Medicine
- Thromboprophylaxis
Background:
- Deep Venous Thrombosis (DVT) is a significant risk following total hip arthroplasty (THA).
- Effective prophylaxis protocols are crucial for patient safety and surgical outcomes.
Purpose of the Study:
- To evaluate the efficacy of a specific DVT prophylaxis protocol in THA patients.
- To compare DVT rates between primary and revision THA surgeries.
Main Methods:
- Retrospective study of 92 patients (110 hips) operated between 2012-2018.
- Implementation of a DVT prophylaxis protocol including low molecular weight heparin, compression devices, and early ambulation.
- DVT detection via clinical evaluation and imaging (radiographs, ultrasound, Doppler), and laboratory tests.
Main Results:
- The DVT prophylaxis protocol demonstrated high efficacy, with only one case (1.09%) of DVT observed.
- The study suggests a low incidence of DVT when the protocol is rigorously followed.
Conclusions:
- Thromboprophylaxis for DVT is indispensable in THA patients.
- The observed low DVT rate (1.09%) underscores the effectiveness of the implemented protocol.
Objective:
To determine the efficacy of Deep Venous Thrombosis (DVT) prophylaxis protocol in patients undergoing total hip arthroplasty (THA), and to verify differences in the rates of this complication when comparing primary replacement surgeries with revision surgeries.
Methods:
We conducted a retrospective study of patients operated between 2012 and 2018, with inclusion and non-inclusion criteria determined by the researchers. A protocol was created to compile data including 92 patients, amounting to 110 operated hips, divided by gender, age, laterality, among other criteria. For THA cases, low molecular weight heparin chemoprophylaxis was used, associated with the use of pneumatic and elastic compression, concomitant to deambulation as soon as possible. The detection of DVT was determined by clinical evaluation and imaging exams such as: simple radiographs, ultrasound, arterial and venous color doppler, and laboratory tests.
Results:
The use of the protocol was very effective in our study. Only one (1.09%) case of deep venous thrombosis was found.
Conclusion:
The use of thromboprophylaxis for DVT is indispensable, as was clearly demonstrated by these cases. We observed only one (1.09%) case of DVT in our series.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management
Venous Thrombosis I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Peripheral Artery Disease V: Postoperative Nursing Management
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...

