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Effect of pupil dilation on intraocular pressure in preterm and term infants

Ayşe Çiçek1, Damla Ergintürk Acar2, Osman Baştuğ3

  • 1Department of Ophthalmology, Kayseri Education and Research Hospital, Kayseri, Turkey.

Arquivos Brasileiros De Oftalmologia
|December 1, 2021
PubMed

Insights

Pupil dilation may unexpectedly alter intraocular pressure in newborns, particularly preterm infants. This finding is crucial for neonatal eye care and monitoring intraocular pressure changes in infants.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Pediatric Medicine

Background:

  • Intraocular pressure (IOP) monitoring is essential in neonatal care.
  • Pupil dilation is a common procedure in ophthalmology, but its effects on IOP in newborns are not fully understood.

Purpose of the Study:

  • To investigate the impact of pupil dilation on intraocular pressure in preterm and term newborns.
  • To determine if gestational age influences the IOP response to mydriatic agents.

Main Methods:

  • A prospective study included 55 eyes of 28 preterm infants (<37 weeks) and 38 eyes of 20 term infants (≥37 weeks).
  • Pupil dilation was achieved using tropicamide 0.5% and phenylephrine 2.5%.
  • Intraocular pressure was measured using the Icare PRO before and after dilation, with paired t-tests for comparison.

Main Results:

  • The mean IOP change was -1.04 ± 3.03 mmHg in preterm infants and -0.39 ± 2.81 mmHg in term infants.
  • A statistically significant IOP alteration was observed in the preterm group post-dilation (p=0.01).

Conclusions:

  • Pupil dilation can cause unexpected changes in intraocular pressure in newborns.
  • Preterm infants appear more susceptible to these IOP alterations following mydriasis.
Abstract

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