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[Cushing's syndrome 1985: current views and possibilities]
Schweizerische Medizinische Wochenschrift
|March 1, 1986
Summary
Cushing
Area of Science:
- Endocrinology
- Oncology
- Neurosurgery
Background:
- Cushing's syndrome is primarily caused by ACTH-producing pituitary microadenomas.
- Rare causes include functional pituitary/hypothalamic disturbances and ectopic corticotropin-releasing factor (CRF) production.
Purpose of the Study:
- To review the diagnosis and management of Cushing's syndrome.
- To highlight the role of diagnostic tools and current therapeutic options.
Main Methods:
- Review of current literature on Cushing's syndrome.
- Analysis of diagnostic criteria and treatment modalities.
Main Results:
- Abnormal adrenocortical function tests remain the most reliable diagnostic method.
- Plasma ACTH levels and imaging (CT scans) aid in differentiating causes.
- Various chemotherapies are available, but surgical tumor removal is preferred.
Conclusions:
- Surgical resection of ACTH- or cortisol-producing tumors is the primary treatment for Cushing's syndrome.
- Accurate diagnosis relies on a combination of biochemical tests and imaging.
- Understanding the etiology is crucial for effective management.