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Updated: Oct 11, 2025

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Treatment Modalities for Anastomotic Leakage in Rectal Cancer Surgery
Deborah S Keller1, K Talboom2, C P M van Helsdingen2
1Division of Colorectal Surgery, Department of Surgery, University of California at Davis Medical Center, Sacramento, California.
Abstract:
Despite advances in rectal cancer surgery, anastomotic leakage (AL) remains a common complication with a significant impact on patient recovery, health care costs, and oncologic outcomes. The spectrum of clinical severity associated with AL is broad, and treatment options are diverse with highly variable practices across the colorectal community. To be effective, the treatment must match not only the patient's current status but also the type of leak, the surgeon's skill, and the resources available. In this chapter, we will review the current and emergent treatment modalities for AL after rectal cancer surgery.
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