Chorea in Neuro-Behçet's Disease.

Area of Science:

• Neurology
• Immunology
• Rheumatology

Background:

• Behçet's disease (BD) is a multisystemic inflammatory disorder.
• Neuro-Behçet's disease (NB) affects the central nervous system in 10-25% of BD cases.
• Chorea, a hyperkinetic movement disorder, is rarely reported in NB.

Observation:

• This study presents a rare case of parenchymal neuro-Behçet's disease.
• The patient exhibited chorea as a neurological manifestation.
• Radiological findings showed lesions in the basal ganglia and periventricular white matter.

Findings:

• The case demonstrates chorea as a rare manifestation of parenchymal NB.
• The variability in chorea's evolution in NB is noted.
• Parenchymal involvement in NB can present with hyperkinetic movement disorders.

Implications:

• Highlights the importance of considering NB in patients with unexplained chorea.
• Suggests further research into the pathophysiology of neurological involvement in BD.
• Emphasizes the diverse clinical spectrum of neuro-Behçet's disease.