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Related Experiment Video

Updated: Oct 11, 2025

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Chorea in Neuro-Behçet's Disease.

Mohamed Hamid1, Kadira Adan1, Amal Satte2

  • 1Department of Neurology, Mohamed V Military Teaching Hospital, Mohamed V University, Rabat, MAR.

Cureus
|December 2, 2021
PubMed
Summary

Behçet's disease (BD) can affect the central nervous system, leading to rare hyperkinetic movement disorders like chorea. This case highlights a rare presentation of neuro-Behçet's disease (NB) involving parenchymal brain lesions and chorea.

Keywords:
basal gangliachoreacyclophosphamidemovement disordersneuro-behcet’s disease

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Area of Science:

  • Neurology
  • Immunology
  • Rheumatology

Background:

  • Behçet's disease (BD) is a multisystemic inflammatory disorder.
  • Neuro-Behçet's disease (NB) affects the central nervous system in 10-25% of BD cases.
  • Chorea, a hyperkinetic movement disorder, is rarely reported in NB.

Observation:

  • This study presents a rare case of parenchymal neuro-Behçet's disease.
  • The patient exhibited chorea as a neurological manifestation.
  • Radiological findings showed lesions in the basal ganglia and periventricular white matter.

Findings:

  • The case demonstrates chorea as a rare manifestation of parenchymal NB.
  • The variability in chorea's evolution in NB is noted.
  • Parenchymal involvement in NB can present with hyperkinetic movement disorders.

Implications:

  • Highlights the importance of considering NB in patients with unexplained chorea.
  • Suggests further research into the pathophysiology of neurological involvement in BD.
  • Emphasizes the diverse clinical spectrum of neuro-Behçet's disease.