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Streak artefacts in Computed Tomography Urography: Comparative evaluation between two different iodinated contrast
Pasquale Pedote1, Monica Cozzolino1, Martina Nicolardi1
1Section of Diagnostic Imaging, Interdisciplinary Department of Medicine, University of Bari 'Aldo Moro', Bari, Italy.
Journal of Medical Imaging and Radiation Oncology
|December 2, 2021
Summary
Iodixanol contrast agent caused more frequent and severe streak artifacts in CT urography compared to Iomeprol. This indicates Iomeprol may be preferable for reducing imaging artifacts in urinary tract CT scans.
Area of Science:
- Radiology
- Medical Imaging
- Urology
Background:
- Streak artifacts in computed tomography (CT) urography can impair diagnostic accuracy.
- Contrast agents with varying iodine concentration and osmolarity may influence artifact generation.
Purpose of the Study:
- To compare the frequency and severity of urinary tract streak artifacts between two contrast agents: Iodixanol and Iomeprol.
- To evaluate the impact of iodine concentration and osmolarity on CT urography artifact formation.
Main Methods:
- Retrospective analysis of 144 adult CT urography scans with excretory renal phase.
- Evaluation by three expert radiologists for streak artifacts in the urinary tract.
- Patients received either Iodixanol (320 mgI/mL) or Iomeprol (400 mgI/mL).
Main Results:
- Iodixanol (83.1%) showed a higher frequency of streak artifacts than Iomeprol (35.6%).
- Marked artifacts were more common with Iodixanol (55.9%) compared to Iomeprol (27%).
- Mean contrast density in the renal pelvis was significantly higher with Iodixanol (2565.6 HU) than Iomeprol (1666 HU).
Conclusions:
- Iodixanol induces a significantly higher frequency and burden of streak artifacts in CT urography compared to Iomeprol.
- The observed differences are attributed to variations in iodine concentration and osmolarity between the contrast agents.
- Iomeprol appears to be associated with fewer artifacts, potentially offering better image quality in urinary tract imaging.
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