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Related Experiment Video

Updated: Oct 11, 2025

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
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[Orthostatic tremor].

Bart E K S Swinnen1,2, Rob M A de Bie1, A F van Rootselaar1

  • 1Amsterdam UMC locatie AMC, afd. Neurologie en Klinische Neurofysiologie, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde
|December 2, 2021
PubMed
Summary
This summary is machine-generated.

Orthostatic tremor causes difficulty standing still and is often underdiagnosed. Early suspicion and neurological referral with tremor registration can aid in diagnosing this rare condition.

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Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Orthostatic tremor (OT) is a rare neurological disorder.
  • Characterized by difficulty maintaining a still stance.
  • Often involves a lengthy diagnostic process and physician unfamiliarity.

Observation:

  • A 72-year-old male presented with a decade of difficulty standing, leg tingling, trembling, and pain.
  • Initial diagnoses were varied, including orthopedic and neurological conditions.
  • A 'helicopter sign' on leg muscle auscultation and a 14 Hz tremor upon standing confirmed OT.

Findings:

  • Tremor registration is crucial for diagnosing orthostatic tremor.
  • Pharmacological treatment can offer moderate symptom improvement.
  • The 'helicopter sign' may be an indicator for further investigation.

Implications:

  • Increased physician awareness of orthostatic tremor is needed.
  • Suspect OT in patients with unexplained instability or atypical symptoms when standing.
  • Neurological referral and specialized tremor analysis are recommended for accurate diagnosis.