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Updated: Oct 11, 2025

Synovial Fluid Analysis to Identify Osteoarthritis
Published on: October 20, 2022
[Various manifestations of calcium pyrophosphate-associated arthritis]
Dieneke A Haverkort1,2, Steven C van Bokhoven3, Annemiek A M E Stenger1
1Sint Maartenskliniek, afd. Reumatologie, Nijmegen.
Abstract:
In calcium pyrophosphate (CPP)-associated arthritis, deposits of calcium pyrophosphate lead to acute attacks of painful joint inflammation. The disease may present with signs of systemic inflammation such as fever, mimicking an infectious disease. Early recognition and treatment of this disease can prevent overdiagnosis and joint damage. In this article we describe three different patient cases of CPP-associated arthritis. The diversity of clinical presentation in CPP-associated arthritis can be of interest to different medical specialties who will occasionally encounter them in daily practice.
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