Related Experiment Video
Updated: Oct 11, 2025

In Situ SIMS and IR Spectroscopy of Well-defined Surfaces Prepared by Soft Landing of Mass-selected Ions
Published on: June 16, 2014
Surface Menshutkin SN2 Reaction on Basic Gold Clusters Provides Novel Opportunities for the Cationization and
Kunihiro Narita1, Yohei Ishida1, Shuichi Nukui1
1Division of Material Science and Engineering, Faculty of Engineering, Hokkaido University, Kita 13 Nishi 8, Kita-ku, Sapporo, Hokkaido 060-8628, Japan.
Abstract:
Surface chemical reactions on atomically precise metal clusters have considerable attention for opening a new platform for cluster functionalization. In this study, basic Au25(4-PyET)18 (4-PyET = -SCH2CH2Py; Py = pyridyl) clusters were successfully transformed into cationized Au25(4-PyET-CH3+)(4-PyET)18- clusters, without altering their Au25 cores, through the Menshutkin SN2 reaction of their surface Py moieties. This study offers not only a simple cationization method but also a protocol for modifying the surface functionalities of molecular metal clusters via a synthetic reaction.
More Related Videos
Related Concept Videos
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Complexation Equilibria: The Chelate Effect
Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions
Reduction of Alkenes: Asymmetric Catalytic Hydrogenation
The metal catalyst used can be either heterogeneous or homogeneous. When hydrogenation of an alkene generates a chiral center, a pair of enantiomeric products is expected to form. However, an enantiomeric excess of one of the products can be facilitated using an enantioselective reaction or an...
Acid Halides to Ketones: Gilman Reagent
As shown below, the mechanism proceeds in two steps. First, one of the alkyl groups of the reagent acts as a nucleophile and attacks the acyl carbon of the acid chloride to form a tetrahedral intermediate. This is followed by the reformation of the carbon–oxygen...

