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Published on: September 8, 2023
Characteristics and clinical outcomes of patients hospitalized with laboratory-confirmed COVID-19-Puerto Rico,
Hannah R Volkman1, Janice Pérez-Padilla1, Joshua M Wong1
1U. S. Centers for Disease Control and Prevention, San Juan, Puerto Rico, United States of America.
Insights
This study of hospitalized COVID-19 patients in Puerto Rico found that obesity and diabetes were common. Older adults and those with immune deficiencies faced higher mortality risks.
Area of Science:
- Infectious Diseases
- Public Health
- Epidemiology
Background:
- COVID-19 has disproportionately affected Hispanic populations globally.
- Understanding the specific clinical characteristics and risk factors for severe COVID-19 in Puerto Rico is crucial for targeted public health interventions.
Purpose of the Study:
- To describe the demographic and clinical features of hospitalized COVID-19 patients in Puerto Rico.
- To identify risk factors associated with poor outcomes, including mortality and intensive care unit (ICU) admission.
Main Methods:
- Retrospective review of medical records for 109 hospitalized patients with confirmed COVID-19 across four hospitals in Puerto Rico.
- Data abstraction focused on patient demographics, underlying conditions, clinical course, interventions, and outcomes.
Main Results:
- The median number of underlying conditions per patient was 3, with obesity and diabetes being most prevalent.
- Twenty-eight percent of patients required ICU admission, and 18% died during hospitalization.
- Advanced age (≥65 years) and presence of immune deficiencies were significant risk factors for mortality.
Conclusions:
- Hospitalized COVID-19 patients in Puerto Rico frequently had multiple comorbidities.
- Prompt identification and protection of elderly patients and those with immune deficiencies are vital for reducing COVID-19 mortality in this population.
Abstract:
Hispanics are the majority ethnic population in Puerto Rico where we reviewed charts of 109 hospitalized COVID-19 patients to better understand demographic and clinical characteristics of COVID-19 and determine risk factors for poor outcomes. Eligible medical records of hospitalized patients with confirmed COVID-19 illnesses were reviewed at four participating hospitals in population centers across Puerto Rico and data were abstracted that described the clinical course, interventions, and outcomes. We found hospitalized patients had a median of 3 underlying conditions with obesity and diabetes as the most frequently reported conditions. Intensive care unit (ICU) admission occurred among 28% of patients and 18% of patients died during the hospitalization. Patients 65 or older or with immune deficiencies had a higher risk for death. Common symptoms included cough, dyspnea, and fatigue; less than half of patients in the study reported fever which was less frequent than reported elsewhere in the literature. It is important for interventions within Hispanic communities to protect high-risk groups.
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