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Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples
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Cluster of SARS-CoV-2 Gamma Variant Infections, Parintins, Brazil, March 2021

Juliana F da Silva, Roberto J Esteves, Charlene Siza

    Emerging Infectious Diseases
    |December 2, 2021
    PubMed

    Insights

    The Gamma variant of SARS-CoV-2 raised concerns about reinfection. However, an investigation in the Brazilian Amazon found no evidence of high reinfection rates, suggesting household transmission was more likely.

    Area of Science:

    • Virology
    • Epidemiology
    • Public Health

    Background:

    • The emergence of the SARS-CoV-2 Gamma (P.1) variant in Brazil led to increased case counts.
    • This surge prompted concerns regarding the potential for reinfection in individuals previously infected with SARS-CoV-2.

    Purpose of the Study:

    • To investigate the possibility of high reinfection rates with the SARS-CoV-2 Gamma variant.
    • To understand transmission dynamics within a specific outbreak setting.

    Main Methods:

    • Case investigation within a cluster of coronavirus disease cases.
    • Analysis of transmission patterns in the Brazilian Amazon.

    Main Results:

    • The investigation identified evidence of household transmission of SARS-CoV-2.
    • No significant rates of reinfection were detected among previously infected individuals.

    Conclusions:

    • While the Gamma variant circulated, high rates of reinfection were not observed in this cluster.
    • Household transmission appears to be a significant factor in the spread of SARS-CoV-2 during this period.
    Keywords:
    2019 novel coronavirus diseaseBrazilCOVID-19Gamma variantP.1 variantSARS-CoV-2coronavirus diseasereinfectionrespiratory infectionssevere acute respiratory syndrome coronavirus 2viruseszoonoses

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