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Updated: Oct 11, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
Published on: November 10, 2023
Outbreak of P.3 (Theta) SARS-CoV-2 emerging variant of concern among service workers in Louisiana
Rebecca Rose1, David J Nolan1, Tessa M LaFleur1
1BioInfoExperts, LLC, Thibodaux, LA, USA.
Abstract:
During routine industrial quarantine/premobilization procedures, four individuals who recently traveled from the Philippines tested positive for SARS-CoV-2. Subsequent genomic analysis showed that all four were infected with a relatively rare Variant of Interest (P.3, Theta) derived from a single origin. This demonstrates the importance of on-going genomic surveillance of SARS-CoV-2.
Insights
Four travelers from the Philippines tested positive for SARS-CoV-2, infected with the P.3 (Theta) variant. This highlights the critical need for continuous genomic surveillance of the virus.
Area of Science:
- Virology
- Genomic Surveillance
- Infectious Diseases
Background:
- Routine quarantine procedures are essential for controlling infectious disease spread.
- The emergence of SARS-CoV-2 variants necessitates vigilant monitoring.
- International travel poses a risk for the introduction of novel viral strains.
Purpose of the Study:
- To report the detection of a rare SARS-CoV-2 variant in returning travelers.
- To emphasize the importance of genomic surveillance in public health.
- To identify the origin and spread of SARS-CoV-2 variants.
Main Methods:
- Case detection during industrial quarantine.
- Genomic sequencing and analysis of SARS-CoV-2 positive samples.
- Phylogenetic analysis to determine variant origin.
Main Results:
- Four individuals who traveled from the Philippines tested positive for SARS-CoV-2.
- All four cases were infected with the P.3 (Theta) variant.
- Genomic analysis indicated a single origin for these P.3 variant infections.
Conclusions:
- Ongoing genomic surveillance is crucial for detecting and managing emerging SARS-CoV-2 variants.
- The P.3 (Theta) variant's detection underscores the need for robust international health screening.
- Early identification of variants aids in implementing timely public health interventions.
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